Endocrine Abstracts

Background: Central obesity in polycystic ovary syndrome (PCOS) is associated with increased inflammatory markers and increased risk for type 2 diabetes.Aim: To evaluate the long-term effects of metformin (M) and/or oral contraceptives (OC) on fat mass.Research design: Randomized, controlled study.Setting: Outpatient clinic.Methods: 90 patients with PCOS were randomized to 12 months M (...

Background: Clinical manifestations, metabolic risk factors and diabetes risk may differ in ethnical subgroups of women with PCOS.Material and methods: A total of 1010 premenopausal women were referred with the diagnoses hirsutism or PCOS during 1997–2008. The patients underwent clinical evaluation, hormone analyses and transvaginal ultrasound (US). Oral glucose tolerance tests (OGTT) (n=500) and ACTH tests (n=434) were performed in a ...

Background: Polycystic ovary syndrome (PCOS) is associated with obesity and increased risk of type 2 diabetes mellitus.Aim: The aim of the present prospective cohort study was to investigate possible associations between PCOS and obstetric outcomes in 199 Danish women with PCOS and 995 controls and to describe the impact of different PCOS phenotypes on the risk of adverse obstetric outcomes.Methods: Women diagnosed with PCOS at Ode...